Abstract: In order to quantitatively evaluate urban karst collapse disaster, based on detailed analysis of the geological conditions,the karst collapse susceptibility in Xuzhou City was evaluated by using eight disaster indicators such as the degree of karst development,covering layer lithology, hydrodynamic condition and etc. By applying the method of analytic hierarchy process-fuzzy comprehensive evaluation,the susceptibility zoning and mapping of karst collapse assessment in the study area was achieved. Results show that the karst collapse grade of Xuzhou can be presented by four categories of susceptibility including high, medium, low and no. The regions which have high karst collapse grade are mainly located in the Solvent factory-Xinsheng street and Denglou water plants-Liangtang water plants in Zhangji water source. The karst water fluctuates near the bedrock surface for a long time, which leading to the karst collapses. So in high collapse prone districts,we should strengthen the exploitation of karst groundwater control, establish karst subsidence monitoring and early warning system and prevent the happening of the karst collapse.